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There is a legend in Japan that if one eats the flesh of a mermaid, one will become immortal. This anime recounts the story of Yuhta and Mana, an immortal boy and girl, and their experiences with a family struggling to achieve immortality at any cost.

Its central characters are a vampire girl named Miyu and her demonic companion Larva. Miyu is the daughter of both a human and a shinma (demon) and as such she was awakened as the guardian whose destiny is to hunt down all stray shinma and send them back to the darkness.